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| Medical news |
A study published in the March 2004 issue of Medical Science Monitor reported that 2 tablespoons a day of olive oil added to an otherwise unchanged diet in 28 outpatients, ranging in age from 64 to 71, resulted in significant drops in total- and LDL cholesterol. Mean concentrations of total cholesterol were lowered by 0.818 mmol/L, and mean concentrations of LDL dropped 0.782 mmol/L. Plus, subjects ratio of HDL:LDL greatly improved; they ended up with higher amounts of protective HDL in relation to lower amounts of dangerous LDL cholesterol.
Three other recent studies (Valavanidis et al.; Morella et al.; Masella et al., see references below) suggest that such heart-healthy effects from olive oil are due not only to its high content of monounsaturated fats, but also to its hefty concentration of antioxidants, including chlorophyll, carotenoids and the polyphenolic compounds tyrosol, hydrotyrosol and oleuropein-all of which not only have free radical scavenging abilities, but protect the vitamin E (alpha-tocopherol) also found in olive oil.
Greek scientists at the University of Athens reporting their research in the April 2004 issue of the Journal of Agriculture and Food Chemistry believe the synergy of all these beneficial nutrients is what is responsible for olive oil's contribution to the health benefits of the Mediterranean diet, a hypothesis supported by Italian research published in the April 2004 issue of the Journal of Nutrition.
In this study, scientists found that the phenols in olive oil have very potent antioxidant effects. The protective effects exerted by extra virgin olive oil biophenols, namely, protocatechuic acid and oleuropein, against LDL oxidation included:
- completely preventing LDL's oxidation when placed in a medium containing macrophage-like cells (in the arteries, arteriosclerosis begins when macrophages damage LDL, starting the development of foam cells that infiltrate the lining of the artery and begin plaque formation)
- inhibiting the production of two powerful oxidants that would normally have been produced and would have damaged LDL, thus preventing the expected decrease in glutathione, a powerful antioxidant the body produces to disarm oxidants (also called free radicals)
- restoring to normal levels the protective activities of two free radical-disarming enzymes that contain glutathione: glutathione reductase and glutathione peroxidase
- inducing higher than normal production and activity of both of these glutathione-containing enzymes.(June 3, 2004)
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